The House of Mendoza is a prominent noble family in Spain, particularly known for its influence during the late Middle Ages and the Renaissance. Originating in the region of Castile, the family played a significant role in the political and military affairs of the time, producing several notable figures, including military leaders and statesmen. Members of the House of Mendoza were often patrons of the arts and contributed to the cultural development of Spain. Their legacy includes impressive architectural works, such as the Palace of the Dukes of Infantado in Guadalajara, which showcases the family's wealth and status throughout history.