The House of Guzmán is a noble lineage that originated in Spain during the Middle Ages. It is known for its significant influence in the regions of Castile and Leon. The family played a crucial role in the political and military affairs of the time, often aligning with the monarchy. Members of the House of Guzmán have held various titles, including dukes and counts, and have been involved in numerous historical events. The family's legacy includes contributions to art, culture, and governance, making it an important part of Spanish history.