Herbicide resistance occurs when weeds evolve to survive applications of herbicides that once effectively controlled them. This resistance can develop through genetic mutations or by selecting for naturally resistant individuals within a weed population. As a result, farmers may struggle to manage these resistant weeds, leading to increased costs and reduced crop yields. The widespread use of certain herbicides, such as glyphosate, has contributed to the rise of herbicide-resistant weeds. To combat this issue, integrated weed management strategies are recommended, which may include crop rotation, mechanical weeding, and the use of multiple herbicide modes of action to reduce reliance on any single herbicide.