MMP-2, or Matrix Metalloproteinase-2, is an enzyme that plays a crucial role in the breakdown of extracellular matrix components. It is involved in various physiological processes, including tissue remodeling, wound healing, and embryogenesis. MMP-2 specifically targets collagen, a key protein in connective tissues, helping to maintain the balance between tissue formation and degradation. This enzyme is produced by several cell types, including fibroblasts and endothelial cells. Dysregulation of MMP-2 activity has been linked to various diseases, such as cancer and cardiovascular disorders, where excessive matrix degradation can lead to tissue damage and disease progression. Understanding MMP-2's function is essential for developing potential therapeutic strategies.