Fibronectin is a high-molecular-weight glycoprotein found in the extracellular matrix and blood plasma. It plays a crucial role in cell adhesion, growth, migration, and differentiation. Fibronectin helps cells attach to one another and to the surrounding matrix, facilitating tissue repair and development.
This protein exists in two main forms: soluble fibronectin in the bloodstream and insoluble fibronectin in tissues. It is composed of multiple domains that allow it to bind to various molecules, including collagen, integrins, and fibrin. These interactions are essential for maintaining the structural integrity of tissues and promoting healing processes.