Fibrodysplasia Ossificans Progressiva
Fibrodysplasia Ossificans Progressiva (FOP) is a rare genetic disorder characterized by the abnormal growth of bone in muscles, tendons, and other connective tissues. This condition leads to the formation of extra-skeletal bone, which can restrict movement and cause significant disability over time. FOP is caused by a mutation in the ACVR1 gene, which plays a role in bone development.
Individuals with FOP often experience flare-ups after minor injuries, resulting in painful swelling and the eventual transformation of soft tissue into bone. There is currently no cure for FOP, and treatment focuses on managing symptoms and preventing complications. Research is ongoing to better understand this condition and develop potential therapies.