Familial Adenomatous Polyposis (FAP)
Familial Adenomatous Polyposis (FAP) is a genetic disorder characterized by the development of numerous polyps in the lining of the colon and rectum. These polyps typically begin to appear in adolescence or early adulthood and have a high potential to become cancerous if not treated. FAP is caused by mutations in the APC gene, which plays a crucial role in cell growth and division.
Individuals with FAP often require regular screenings and may undergo preventive surgeries, such as a colectomy, to reduce the risk of colorectal cancer. Family members of affected individuals may also be tested for the APC gene mutation to assess their risk of developing the condition. Early detection and management are essential for improving outcomes.