Familial Mediterranean Fever (FMF) is a genetic disorder that primarily affects people of Mediterranean descent, including those of Jewish, Arab, and Armenian backgrounds. It is characterized by recurrent episodes of fever and inflammation, often accompanied by abdominal pain, chest pain, or joint pain. These episodes can last from a few hours to several days and may occur at irregular intervals. FMF is caused by mutations in the MEFV gene, which plays a role in regulating inflammation. Diagnosis typically involves clinical evaluation and genetic testing. Treatment often includes the use of colchicine, a medication that helps reduce the frequency and severity of attacks, improving the quality of life for those affected.