Exacerbation refers to the worsening or intensification of a condition or symptom. It is commonly used in medical contexts to describe situations where a chronic illness, such as asthma or chronic obstructive pulmonary disease (COPD), becomes more severe. Factors like infections, environmental changes, or non-compliance with treatment can trigger exacerbations. In addition to physical health, exacerbation can also apply to emotional or psychological conditions, such as anxiety or depression. Stressful life events or changes in medication can lead to an increase in symptoms, making it essential for individuals to manage their conditions effectively to minimize the risk of exacerbation.