The Duke of Mecklenburg refers to the title held by the rulers of the historical region of Mecklenburg in northern Germany. This title has a long history, dating back to the 12th century, when the region was divided into various principalities. The Dukes played a significant role in the political landscape of northern Europe, often engaging in alliances and conflicts with neighboring states. The most notable dukes include Duke Heinrich, who was influential in the 14th century, and Duke Christian, who ruled in the 18th century. The title eventually became part of the larger Grand Duchy of Mecklenburg-Schwerin and Mecklenburg-Strelitz, which were established in the 19th century.