Dubin-Johnson Syndrome is a rare genetic disorder that affects the liver's ability to process bilirubin, a substance produced during the breakdown of red blood cells. This condition is caused by a mutation in the ABCC2 gene, which leads to an accumulation of conjugated bilirubin in the bloodstream. Individuals with this syndrome often have a mild increase in bilirubin levels but typically do not experience severe symptoms. Most people with Dubin-Johnson Syndrome lead normal lives and may not require treatment. Diagnosis is usually made through blood tests that reveal elevated bilirubin levels, and liver function tests are often normal. The condition is generally benign and does not lead to serious liver disease.