Connective tissue disorders are a group of medical conditions that affect the tissues that support, bind, or separate other tissues and organs in the body. These disorders can impact the skin, joints, blood vessels, and organs, leading to symptoms such as pain, stiffness, and swelling. Common examples include Ehlers-Danlos syndrome, lupus, and rheumatoid arthritis. The exact cause of connective tissue disorders can vary, with some being genetic and others resulting from autoimmune responses. Diagnosis often involves a combination of physical examinations, medical history, and laboratory tests. Treatment typically focuses on managing symptoms and may include medications, physical therapy, or lifestyle changes.