Coltivirus is a type of virus that belongs to the family of Reoviridae. It is primarily known for causing diseases in certain species of mammals, particularly rodents. The virus is transmitted through the bites of infected ticks, which can lead to various health issues in the host. One of the most studied strains of Coltivirus is the Colorado tick fever virus, which can cause flu-like symptoms in humans. While most infections are mild, severe cases can lead to complications such as hemorrhagic fever. Research continues to better understand its transmission and effects on both wildlife and humans.