Chronic Granulomatous Disease (CGD) is a rare genetic disorder that affects the immune system. Individuals with CGD have difficulty fighting off certain bacterial and fungal infections due to a defect in their phagocytes, which are white blood cells that help eliminate pathogens. This condition leads to the formation of granulomas, which are clusters of immune cells that form in response to chronic inflammation. People with CGD may experience recurrent infections, particularly from organisms like Staphylococcus and Aspergillus. Diagnosis typically involves blood tests to assess the function of neutrophils, a type of phagocyte. Treatment often includes antibiotics and antifungal medications to prevent infections, along with potential therapies to boost the immune response.