Caveolin-3 is a protein primarily found in muscle cells, particularly in cardiac and skeletal muscle. It plays a crucial role in the formation of small invaginations in the cell membrane called caveolae, which are involved in various cellular processes, including signal transduction and lipid regulation. Mutations in the Caveolin-3 gene can lead to muscle disorders, such as Limb-Girdle Muscular Dystrophy and Dilated Cardiomyopathy. These conditions can affect muscle strength and heart function, highlighting the importance of Caveolin-3 in maintaining healthy muscle tissue and overall cellular function.