Caveolins
Caveolins are a family of proteins that play a crucial role in the formation of small invaginations in the cell membrane known as caveolae. These structures are involved in various cellular processes, including endocytosis, signal transduction, and lipid regulation. Caveolins are primarily found in adipocytes (fat cells) and endothelial cells, where they help maintain cellular structure and function.
There are three main types of caveolins: Caveolin-1, Caveolin-2, and Caveolin-3. Each type has distinct roles in different tissues. For example, Caveolin-3 is primarily expressed in muscle cells and is important for muscle function. Dysregulation of caveolins has been linked to various diseases, including cancer and cardiovascular disorders.