Caspase-1 is an enzyme that plays a crucial role in the immune system. It is part of a group of proteins known as caspases, which are involved in the process of inflammation and cell death. Specifically, Caspase-1 is responsible for activating inflammatory cytokines, such as IL-1β and IL-18, which help the body respond to infections and injuries. This enzyme is primarily activated in response to pathogens and cellular stress. By processing these cytokines, Caspase-1 helps to initiate an inflammatory response, which is essential for fighting off infections. Dysregulation of Caspase-1 activity can lead to various inflammatory diseases, highlighting its importance in maintaining health.