Cafe-au-lait spots are light brown skin markings that can appear anywhere on the body. They are usually flat and oval-shaped, resembling the color of coffee with milk. These spots are common in people of all ethnic backgrounds and can vary in size. While Cafe-au-lait spots are generally harmless, having six or more spots larger than 5 millimeters in diameter may indicate a genetic condition called neurofibromatosis. It is important to monitor these spots and consult a healthcare professional if there are any changes or concerns.