CMT, or Charcot-Marie-Tooth disease, is a group of inherited disorders that affect the peripheral nerves, which are responsible for sending signals between the brain and the rest of the body. This condition leads to muscle weakness, atrophy, and sensory loss, primarily in the feet and hands. Symptoms often begin in adolescence or early adulthood, but they can appear at any age. The disease is caused by genetic mutations that affect the structure and function of nerve cells. There are several types of CMT, with varying degrees of severity and symptoms. While there is currently no cure, treatments such as physical therapy and orthotic devices can help manage symptoms and improve quality of life.