Chronic Myeloid Leukemia (CML) is a type of cancer that affects the blood and bone marrow. It occurs when the body produces too many abnormal white blood cells, which can crowd out healthy cells. CML is often associated with a genetic mutation known as the Philadelphia chromosome, which plays a key role in its development. Symptoms of CML can include fatigue, fever, night sweats, and an enlarged spleen. Diagnosis typically involves blood tests and bone marrow examinations. Treatment options may include targeted therapies, such as imatinib, which specifically target the cancerous cells while minimizing damage to normal cells.