Black Mesa is a fictional research facility featured in the video game series Half-Life. It is located in New Mexico and is known for its advanced scientific experiments, particularly in the field of quantum physics. The facility becomes infamous after a catastrophic accident during an experiment, leading to an alien invasion. The game's storyline follows Gordon Freeman, a theoretical physicist who must navigate the chaos unleashed by the accident. Players encounter various challenges, including combat with alien creatures and military personnel sent to contain the situation. Black Mesa serves as a central setting for the game's exploration of science and its unintended consequences.