Avermectins are a group of medications derived from a soil bacterium called Streptomyces avermitilis. They are primarily used to treat parasitic infections in both humans and animals. These compounds work by disrupting the nervous system of parasites, leading to their paralysis and death. Avermectins are commonly used in veterinary medicine to control worms and external parasites like lice and mites. In addition to their veterinary applications, avermectins have also been effective in treating certain human conditions, such as river blindness and lymphatic filariasis. Their ability to target specific parasites makes them valuable in public health efforts, especially in regions where these diseases are prevalent.