Artemisinin-based combination therapies (ACTs) are a group of medications used to treat malaria, a disease caused by parasites transmitted through mosquito bites. ACTs combine artemisinin, derived from the sweet wormwood plant, with another antimalarial drug to enhance effectiveness and reduce the risk of resistance. These therapies are recommended by the World Health Organization (WHO) as the first-line treatment for uncomplicated malaria. By using two different mechanisms of action, ACTs help to quickly reduce the number of parasites in the bloodstream, leading to faster recovery and improved patient outcomes.