Arginase II is an enzyme that plays a crucial role in the urea cycle, which helps remove excess nitrogen from the body. It is primarily found in the mitochondria of cells, particularly in the liver and kidneys. This enzyme converts arginine, an amino acid, into ornithine and urea, facilitating the elimination of nitrogen waste. In addition to its role in detoxification, Arginase II is involved in regulating nitric oxide production and can influence various physiological processes, including blood flow and immune responses. Dysregulation of this enzyme has been linked to several health conditions, including cardiovascular diseases and metabolic disorders.