Arachidonic Acid Metabolism
Arachidonic acid is a polyunsaturated fatty acid found in cell membranes. It plays a crucial role in the metabolism of eicosanoids, which are signaling molecules that influence inflammation, immunity, and other physiological processes. The metabolism of arachidonic acid primarily occurs through enzymatic pathways involving cyclooxygenases (COX) and lipoxygenases (LOX), leading to the production of prostaglandins, thromboxanes, and leukotrienes.
These eicosanoids have various functions, such as regulating blood flow, promoting platelet aggregation, and mediating inflammatory responses. The balance of arachidonic acid metabolism is essential for maintaining health, as dysregulation can contribute to conditions like asthma, arthritis, and cardiovascular diseases.