Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord. It leads to the gradual loss of muscle control, resulting in weakness, difficulty speaking, and eventually paralysis. The exact cause of ALS is not fully understood, but genetic and environmental factors may play a role. Symptoms of ALS can vary widely among individuals but often include muscle twitching, cramping, and difficulty with fine motor skills. While there is currently no cure for ALS, treatments are available to help manage symptoms and improve quality of life. Research is ongoing to better understand the disease and develop effective therapies.