The expression "4(4 + 1)" involves basic arithmetic operations, specifically multiplication and addition. To solve it, you first need to evaluate the expression inside the parentheses, which is 4 + 1. This equals 5. Next, you multiply the result by 4. So, you calculate 4 × 5, which equals 20. Therefore, the final result of the expression "4(4 + 1)" is 20. This demonstrates how to use the order of operations in mathematics, where calculations inside parentheses are performed first.