3α-Hydroxysteroid Dehydrogenase is an enzyme that plays a crucial role in the metabolism of steroid hormones. It catalyzes the conversion of 3α-hydroxysteroids into 3-ketosteroids, which is essential for the regulation of various physiological processes, including the synthesis of androgens and estrogens. This enzyme is found in various tissues, including the liver and brain, and is involved in the metabolism of hormones like testosterone and cortisol. Dysregulation of 3α-Hydroxysteroid Dehydrogenase can lead to hormonal imbalances and is associated with certain medical conditions, including adrenal disorders.