The thyroid hormone receptor is a protein that binds to thyroid hormones, such as thyroxine (T4) and triiodothyronine (T3). These receptors are found in various tissues throughout the body and play a crucial role in regulating metabolism, growth, and development. When thyroid hormones attach to these receptors, they influence gene expression, leading to various physiological effects. There are two main types of thyroid hormone receptors, known as TRα and TRβ. Each type has different functions and is distributed in different tissues. Proper functioning of these receptors is essential for maintaining overall health, as imbalances can lead to conditions like hypothyroidism or hyperthyroidism.