Systemic sclerosis, also known as scleroderma, is a rare autoimmune disease characterized by the hardening and tightening of the skin and connective tissues. It occurs when the body produces too much collagen, leading to fibrosis, which can affect various organs, including the lungs, heart, and kidneys. Symptoms may include skin changes, joint pain, and digestive issues. There are two main types of systemic sclerosis: limited scleroderma and diffuse scleroderma. Limited scleroderma primarily affects the skin and has a slower progression, while diffuse scleroderma can rapidly impact internal organs. Early diagnosis and management are crucial for improving quality of life and outcomes.