spheronization
Spheronization is a pharmaceutical process used to create spherical pellets from granules. This technique improves the flow and uniformity of the material, making it easier to handle and process. The process typically involves the use of a spheronizer, which rotates the granules and subjects them to friction and shear forces, resulting in the formation of round particles.
The resulting spherical pellets can enhance drug release and absorption in the body. Spheronization is commonly applied in the production of controlled-release formulations, where consistent dosing is crucial. This method is also beneficial in the production of nutraceuticals and food additives.