single-strand binding proteins
Single-strand binding proteins (SSBs) are essential molecules that stabilize single-stranded DNA during processes like DNA replication and repair. When the double helix unwinds, SSBs attach to the exposed strands, preventing them from re-annealing or forming secondary structures. This stabilization is crucial for the proper functioning of enzymes involved in DNA synthesis.
These proteins play a vital role in maintaining the integrity of the genetic material. By keeping the DNA strands apart, SSBs ensure that other proteins, such as DNA polymerase, can access the template strand to synthesize new DNA. Their function is critical for accurate and efficient cellular processes.