The term "sanctum sanctorum" is derived from Latin, meaning "holy of holies." It traditionally refers to the innermost and most sacred area of a temple, particularly in ancient religious contexts. In the context of the Hebrew Bible, it describes the inner chamber of the Temple of Solomon, where the Ark of the Covenant was kept, symbolizing the presence of God. In modern culture, "sanctum sanctorum" is often associated with the fictional character Doctor Strange from Marvel Comics. His residence, also called the Sanctum Sanctorum, serves as a mystical sanctuary filled with magical artifacts and serves as a base for his superhero activities.