Post-weaning multisystemic wasting syndrome (PWMSWS) is a disease that primarily affects young pigs, particularly those weaned from their mothers. It is characterized by a significant loss of weight, poor growth, and various health issues. The condition is often linked to infections caused by the porcine circovirus type 2 (PCV2), which can weaken the pig's immune system. The syndrome can lead to increased mortality rates in affected herds, making it a concern for pig farmers. Management practices, including vaccination against PCV2 and maintaining good hygiene, are essential to prevent and control PWMSWS in swine production.