Phosphoglucose isomerase is an enzyme that plays a crucial role in carbohydrate metabolism. It catalyzes the reversible conversion of glucose-6-phosphate to fructose-6-phosphate, which is an important step in the glycolysis and gluconeogenesis pathways. This reaction helps cells efficiently utilize glucose for energy production. In addition to its metabolic functions, phosphoglucose isomerase also has roles in other biological processes. It can act as a signaling molecule and is involved in cell growth and differentiation. Dysregulation of this enzyme has been linked to various diseases, including certain types of cancer.