Pemphigus foliaceus is an autoimmune skin disorder characterized by the formation of blisters and sores on the skin. It occurs when the immune system mistakenly attacks proteins that help skin cells stick together, leading to the separation of skin layers. This condition primarily affects the outer layer of the skin, resulting in painful, crusty lesions. The blisters in pemphigus foliaceus are typically superficial and can appear on the face, scalp, and chest. Treatment often involves medications that suppress the immune system, such as corticosteroids, to reduce inflammation and prevent new lesions from forming. Early diagnosis and management are crucial for effective control of the disease.