myofibroblasts
Myofibroblasts are specialized cells that play a crucial role in wound healing and tissue repair. They are characterized by their ability to contract and produce extracellular matrix components, which help in the formation of new tissue. Myofibroblasts are derived from various cell types, including fibroblasts and mesenchymal stem cells, and are typically found in areas of injury or inflammation.
In addition to their role in healing, myofibroblasts are also involved in fibrosis, a condition where excessive connective tissue builds up in organs, leading to dysfunction. Their activity is regulated by various growth factors and cytokines, which can influence their proliferation and function in different physiological and pathological contexts.