Mucopolysaccharidosis (MPS) is a group of inherited disorders caused by the body's inability to break down certain long chains of sugar molecules called glycosaminoglycans. This leads to an accumulation of these substances in various tissues, resulting in a range of health problems. Symptoms can vary widely but often include skeletal abnormalities, joint stiffness, and organ dysfunction. There are several types of MPS, each linked to a specific enzyme deficiency. Common types include MPS I, MPS II, and MPS III. Diagnosis typically involves genetic testing and enzyme assays, while treatment options may include enzyme replacement therapy and supportive care to manage symptoms.