Metastatic calcification is a condition where calcium deposits form in various tissues of the body due to elevated levels of calcium in the blood, known as hypercalcemia. This can occur in conditions such as hyperparathyroidism, chronic kidney disease, or malignancies. The excess calcium can lead to the hardening of tissues, affecting their normal function. Unlike dystrophic calcification, which occurs in damaged tissues, metastatic calcification happens in otherwise healthy tissues. Common sites for these deposits include the lungs, kidneys, and blood vessels. The presence of these deposits can lead to complications, depending on their location and extent.