Metallopeptidases are a type of enzyme that play a crucial role in breaking down proteins by cleaving peptide bonds. They require metal ions, such as zinc or cobalt, to function effectively. These enzymes are found in various organisms, including bacteria, plants, and animals, and are involved in numerous biological processes, such as digestion and cellular signaling. These enzymes are classified based on their structure and the specific metal ion they utilize. Metallopeptidases are important in medical research, as they can be linked to various diseases, including cancer and inflammatory conditions. Understanding their mechanisms can lead to the development of targeted therapies.