Magnetic-activated cell sorting (MACS) is a technique used to separate specific cells from a mixed population based on their surface markers. This method involves labeling target cells with magnetic beads that are coated with antibodies specific to those markers. When a magnetic field is applied, the labeled cells are attracted to the magnet, allowing for their isolation from other cells. MACS is widely used in research and clinical applications, such as immunology and stem cell therapy. It enables scientists to obtain pure cell populations for further study or therapeutic use, enhancing the understanding of cellular functions and disease mechanisms.