Magnetic-Activated Cell Sorting (MACS) is a technique used to separate specific cells from a mixture based on their surface markers. This method involves labeling target cells with magnetic beads that bind to specific proteins on the cell surface. When the mixture is passed through a magnetic field, the labeled cells are attracted to the magnet, allowing for their isolation from other cells. MACS is widely used in research and clinical applications, such as immunology and stem cell therapy. It enables scientists to obtain pure populations of cells for further study or therapeutic use, enhancing the understanding of cellular functions and disease mechanisms.