mTORC2
mTORC2 is a protein complex that plays a crucial role in regulating cell growth, metabolism, and survival. It is part of the mTOR (mechanistic target of rapamycin) signaling pathway, which responds to nutrients, growth factors, and stress signals. mTORC2 specifically helps control processes like cell proliferation and the organization of the cytoskeleton, which is essential for maintaining cell shape and movement.
This complex is composed of several proteins, including Rictor and mLST8, and is activated by various signals, such as insulin. Dysregulation of mTORC2 has been linked to several diseases, including cancer and metabolic disorders, making it a significant focus of research in understanding cellular functions and developing potential therapies.