Liposomal amphotericin B is an antifungal medication used primarily to treat serious fungal infections, particularly in immunocompromised patients. It is a formulation of amphotericin B, encapsulated in lipid (fat) layers, which helps to reduce toxicity and improve the drug's effectiveness. This formulation allows for better delivery to the site of infection while minimizing side effects commonly associated with traditional amphotericin B. This medication is often used for conditions such as cryptococcal meningitis and aspergillosis. It is administered intravenously and is preferred in cases where patients may have kidney issues or are at risk of severe side effects from standard treatments.