Lipoprotein lipase (LPL) is an enzyme that plays a crucial role in breaking down fats in the bloodstream. It is primarily found on the walls of blood vessels and helps convert triglycerides, a type of fat, into free fatty acids and glycerol. This process is essential for providing energy to tissues and organs. LPL is activated by apolipoproteins, which are proteins that bind to lipoproteins. The activity of LPL is influenced by various factors, including hormones like insulin. Proper functioning of LPL is important for maintaining healthy lipid levels and preventing conditions such as hyperlipidemia and cardiovascular disease.