Lipid kinases are enzymes that play a crucial role in cellular signaling by adding phosphate groups to lipids, which are fat-like molecules. This process, known as phosphorylation, can alter the function and activity of these lipids, influencing various cellular processes such as growth, survival, and metabolism. These enzymes are important in the regulation of phosphoinositides, a specific class of lipids that are involved in signaling pathways. Dysregulation of lipid kinases can lead to various diseases, including cancer and diabetes, making them potential targets for therapeutic interventions.