Integrase inhibitors are a class of antiviral medications used primarily to treat HIV infections. They work by blocking the action of the integrase enzyme, which is crucial for the virus to insert its genetic material into the host's DNA. By preventing this integration, integrase inhibitors help reduce the viral load in the body and improve the immune system's function. These medications are often part of a combination therapy, which includes other types of antiretroviral drugs. Common examples of integrase inhibitors include raltegravir, dolutegravir, and bictegravir. They are generally well-tolerated and have become a key component in modern HIV treatment regimens.