Epidemic Kaposi's sarcoma is a type of cancer that primarily affects individuals with weakened immune systems, particularly those with HIV/AIDS. It is characterized by the development of tumors in the skin, lymph nodes, and other organs. The lesions often appear as purple or brown spots and can be painful or itchy. This form of Kaposi's sarcoma is linked to the Kaposi's sarcoma-associated herpesvirus (KSHV), which is more prevalent in populations with high rates of HIV. Treatment options may include antiretroviral therapy, chemotherapy, and radiation, aimed at managing symptoms and improving the patient's quality of life.