Dystrophic EB, or dystrophic epidermolysis bullosa, is a rare genetic skin disorder characterized by fragile skin that blisters easily. This condition results from mutations in the genes responsible for producing proteins that help anchor the skin layers together. As a result, individuals with dystrophic EB experience painful blisters and wounds, often leading to scarring and skin infections. There are two main types of dystrophic EB: dominant and recessive. The dominant form is generally milder, while the recessive form can be more severe, affecting not only the skin but also other organs. Management focuses on wound care and preventing infections to improve quality of life.