Cystathionine gamma-lyase is an enzyme that plays a crucial role in the metabolism of sulfur-containing amino acids, particularly in the conversion of cystathionine to cysteine. This process is part of the transsulfuration pathway, which helps regulate levels of homocysteine and contributes to the synthesis of important molecules like glutathione. This enzyme is primarily found in the liver and kidneys and is essential for maintaining proper cellular function. Dysregulation of cystathionine gamma-lyase activity can lead to various health issues, including cardiovascular diseases and metabolic disorders, highlighting its importance in human health.